Filtered By:
Cancer: Gastric (Stomach) Cancer
This page shows you your search results in order of date.
Order by Relevance | Date
Total 20058 results found since Jan 2013.
Taxane-Based Chemotherapy Is Effective in Metastatic Appendiceal Adenocarcinoma
Oncologist. 2023 Sep 20:oyad263. doi: 10.1093/oncolo/oyad263. Online ahead of print.ABSTRACTAppendiceal cancer is a rare, orphan disease with no therapies currently approved by the FDA for its treatment. Given the limited data regarding drug efficacy, these tumors have historically been treated with chemotherapy designed for colon cancer. However, an overwhelming body of molecular data has demonstrated that appendiceal adenocarcinoma is a distinct entity with key molecular differences from colon cancer, notably rare APC mutation. Recognizing that APC loss-of-function is thought to contribute to taxane resistance and that t...
Source: The Oncologist - September 22, 2023 Category: Cancer & Oncology Authors: Julia Dansby Aditya More Mohammad Zeineddine Abdelrahman Yousef Alisha Bent Farshid Dayyani Robert Wolff Michael Overman John Paul Shen Source Type: research
Chemo-immune cell therapy by intratumoral injection of adoptive NK cells with capecitabine in gastric cancer xenograft model
CONCLUSION: Although NK cell therapy could effectively decrease the mitotic count in vivo, the obtained findings indicated lesser potency than MC despite ex vivo activation. In order to enhance NK cell therapy effectiveness, suppressive features of the tumor microenvironment and inhibitory immune checkpoints blockade should be considered.PMID:37736341 | PMC:PMC10509737 | DOI:10.34172/bi.2022.26386
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Zeinab Ghazvinian Shahrokh Abdolahi Mohammad Ahmadvand Amir Hossein Emami Samad Muhammadnejad Hamid Asadzadeh Aghdaei Jafar Ai Mohammad Reza Zali Iman Seyhoun Javad Verdi Kaveh Baghaei Source Type: research
Galectin-3 Cooperates with CD47 to Suppress Phagocytosis and T cell Immunity in Gastric Cancer Peritoneal Metastases
Cancer Res. 2023 Sep 22. doi: 10.1158/0008-5472.CAN-23-0783. Online ahead of print.ABSTRACTThe peritoneal cavity is a common site of gastric adenocarcinoma (GAC) metastasis. Peritoneal carcinomatosis (PC) is resistant to current therapies and confer poor prognosis, highlighting the need to identify new therapeutic targets. CD47 conveys a "don't eat me" signal to myeloid cells upon binding its receptor SIRPα, which helps tumor cells circumvent macrophage phagocytosis and evade innate immune responses. Previous studies demonstrated that the blockade of CD47 alone results in limited clinical benefits, suggesting that other t...
Source: Cell Research - September 22, 2023 Category: Cytology Authors: Yibo Fan Shumei Song Yuan Li Shilpa S Dhar Jiankang Jin Katsuhiro Yoshimura Xiaodan Yao Ruiping Wang Ailing W Scott Melissa Pool Pizzi JingJing Wu Lang Ma George A Calin Samir Hanash Linghua Wang Michael Curran Jaffer A Ajani Source Type: research
Risk factors of post-operation surgical site infection for gastric cancer patients underwent total gastrectomy
Asian J Surg. 2023 Sep 19:S1015-9584(23)01439-2. doi: 10.1016/j.asjsur.2023.09.054. Online ahead of print.NO ABSTRACTPMID:37734985 | DOI:10.1016/j.asjsur.2023.09.054
Source: Asian Journal of Surgery - September 21, 2023 Category: Surgery Authors: Chunhong Mu Ciba Zhu Ting Li Jichun Ma Source Type: research
Population effectiveness of endoscopy screening for mortality reduction in gastric cancer
CONCLUSIONS: In addition to the effectiveness of the used modality, the disease burden and screened rate were important in the population effectiveness of cancer screening. Regarding the high NNSs and the low expected mortality-rate reduction, population-based endoscopic screening seems not to be effective in many countries, and these results are meaningful in decision-making regarding the introduction of endoscopic screening.PMID:37731836 | PMC:PMC10508325 | DOI:10.1002/deo2.296
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Naoki Ishii Yasutoshi Shiratori Masahiro Ishikane Fumio Omata Source Type: research
Lifestyle habits and gastric cancer in an East Asian population: a Mendelian randomization study
CONCLUSIONS: Our study suggests that tea intake may reduce the risk of GC, for which smoking is a potential risk factor. Nevertheless, a larger and more diverse sample size is needed for further validation.PMID:37731647 | PMC:PMC10507616 | DOI:10.3389/fonc.2023.1224753
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Yuegui Tan Zhao Wei Kun Liu Yuzhen Qin Wenqi Hui Source Type: research
Serum basic fibroblast growth factor and interleukin-1 β predict the effect of first-line chemotherapy in patients with advanced gastric cancer
CONCLUSION: The FLOT regimen was effective in reducing the serum CEA, CA199, and TPS levels as well as in improving the 1-year survival rate of patients with good tolerability, making it worthy of clinical promotion and application.PMID:37731570 | PMC:PMC10507556 | DOI:10.12998/wjcc.v11.i26.6083
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Li Zheng Li-Hong Gan Ling Yao Bin Li Ya-Qin Huang Fu-Bao Zhang Meng-Qi Kuang Nian Fang Source Type: research
Identification of stromal cell-derived factor 4 as a liquid biopsy-based diagnostic marker in solid cancers
In conclusion, serum SDF4 levels could be a promising candidate for a novel diagnostic biomarker for GC and other malignancies.PMID:37730904 | DOI:10.1038/s41598-023-42201-2
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Takahiro Shinozuka Mitsuro Kanda Dai Shimizu Shinichi Umeda Hideki Takami Yoshikuni Inokawa Norifumi Hattori Masamichi Hayashi Chie Tanaka Goro Nakayama Yasuhiro Kodera Source Type: research
Left epigastric isolated tumor fed by the inferior phrenic artery diagnosed as ectopic hepatocellular carcinoma: A case report
CONCLUSION: This asymptomatic ectopic HCC case described achieved an excellent result due to early detection, radical resection, and systematic surveillance.PMID:37731571 | PMC:PMC10507550 | DOI:10.12998/wjcc.v11.i26.6231
Source: Clinical Lung Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Hong-Bo Liu Li-Hua Zhao Yong-Jian Zhang Zhi-Feng Li Lei Li Qian-Peng Huang Source Type: research
Exosomal circKIAA1797 Regulates Cell Progression and Glycolysis by Targeting miR-4429/PBX3 Pathway in Gastric Cancer
Biochem Genet. 2023 Sep 20. doi: 10.1007/s10528-023-10529-z. Online ahead of print.ABSTRACTIn recent years, circular RNAs (circRNAs) are extensively studied in the progression of various types of cancer, while the mechanism of circKIAA1797 is rarely studied in gastric cancer (GC). Hence, this research aimed to investigate the expression of exosomal circKIAA1797 and its biological function in GC cells. Exosomes were extracted from the serum of GC patients and identified by transmission electron microscopy (TEM) and nanoparticle tracking analyzer (NTA). CD81, CD63, Bcl-2, Bax, and pre-leukemia transcription factor 3 (PBX3) p...
Source: Biochemical Genetics - September 21, 2023 Category: Genetics & Stem Cells Authors: Xiaomei Zheng Hongwei Xiao Xiaoxiao Liu Ting Huang Chengwei Deng Source Type: research
Frailty and long-term survival of patients with gastric cancer: a meta-analysis
ConclusionFrailty is associated with poor long-term survival of patients with GC.
Source: Frontiers in Oncology - September 21, 2023 Category: Cancer & Oncology Source Type: research
TRPM8 as a Potential Biomarker and Therapeutic Target for Gastric Cancer Identified by a Combination of Text Mining and RNA Sequencing
CONCLUSION: This study provides insights into the underlying role of TRPM8 in cell proliferation. In addition, TRPM8 may be used as a potential therapeutic target for patients with gastric cancer.PMID:37728085 | DOI:10.2174/1566523223666230529142423
Source: Current Gene Therapy - September 20, 2023 Category: Genetics & Stem Cells Authors: Na Kong Wendong Li Jun Zhang Xin Wang Lin Hu Qiqi Xu Source Type: research
Multidimensional Analysis of a Cell-Free DNA Whole Methylome Sequencing Assay for Early Detection of Gastric Cancer: Protocol for an Observational Case-Control Study
CONCLUSIONS: This is the first registered case-control study designed to investigate a stacked ensemble model integrating several cfDNA features generated from a bisulfite-free whole methylome sequencing assay. These features include methylation patterns, fragmentation profiles, and chromosomal copy number changes, with the aim of identifying the GC population. This study will determine whether multidimensional analysis of cfDNA will prove to be an effective strategy for distinguishing patients with GC from nonmalignant individuals within the Chinese population. We anticipate the THEMIS model will complement the standard-o...
Source: Cell Research - September 20, 2023 Category: Cytology Authors: Yongjun Han Jiangpeng Wei Weidong Wang Ruiqi Gao Ning Shen Xiaofeng Song Yang Ni Yulong Li Li-Di Xu Weizhi Chen Xiaohua Li Source Type: research
